Chief Medical Officer (CMO) - (M/F/X)

Working closely with the CEO, CBO and CSO, you integrate clinical medicine, clinical operations, regulatory medicine, pharmacovigilance, medical affairs, publications and commercial medical education. You will also be a visible external representative of Inteliphage in hospitals, clinical societies and the international infectious-disease.

What your days could look like

Clinical strategy completion and execution

• Lead and work closely with our Clinical Advisory Board to define and finalise key clinical questions, including patient populations, sub-indication grouping, endpoints, biomarkers, timing and practical implementation.
• Translate the clinical strategy into regulator-ready and site-executable studies.
• Maintain a coherent route from First-in-Human studies to pivotal development and registration.

Medical affairs and external clinical leadership

• Build Inteliphage’s medical affairs capability.
• Develop relationships with KOLs, regulators, investigators, societies, hospitals and clinical microbiology networks.
• Represent Inteliphage at scientific congresses, advisory boards and expert meetings.
• Lead publication planning and timely dissemination of clinical results in peer-reviewed literature.

Clinical development leadership

• Finalize the Clinical Development Plan, Target Product Profiles and indication-specific evidence plans.
• Lead protocol development, investigator brochures, clinical sections of regulatory dossiers and clinical study reports.
• Oversee Phase I–III execution, including medical monitoring, eligibility decisions, endpoint interpretation and benefit-risk assessment.
• Ensure strong interfaces with clinical operations, statistics, data management, pharmacology, CMC and regulatory affairs.

Medical education for Business Development teams

• Design and deliver structured medical training for Business Development teams.
• Ensure teams understand disease pathways, unmet need, PTMP mechanism and use, clinical evidence, appropriate scientific claims and escalation of medical questions.
• Develop field medical materials and maintain scientific consistency in hospital-facing interactions.

Patient safety and regulatory medicine

• Provide medical oversight of pharmacovigilance and safety management.
• Lead medical contributions to EMA and other authority interactions, ethics committees and clinical trial applications.
• Maintain an evidence-based benefit-risk framework across the product lifecycle.

Medical strategy and governance

• Own and execute the company-wide medical strategy.
• Establish medical governance, safety escalation, evidence review and protocol decision processes.
• Advise the Executive Leadership Team and Board on medical risk, opportunity and development choices.

European clinical partnerships and programme financing

• Convert the existing Clinical Advisory Board and hospital network into trial-specific European consortia for BJI, acute and chronic LRTI.
• Own the clinical rationale, protocol architecture, site model, recruitment assumptions and clinical budgets used in Horizon Europe, IHI and complementary funding applications.
• Identify and medically qualify national, disease-specific and investigator-led funding opportunities that can finance defined components of the five-trial program.
• Ensure that consortium agreements, clinical trial agreements and data-access arrangements provide Inteliphage with the rights required to use the complete clinical evidence package in regulatory submissions.
• Work with the CEO, CBO, CSO, Finance, Regulatory and program-management functions to elaborate and monitor funding plans

What you bring to the table

Education and clinical credentials

• Medical degree with specialist training in infectious diseases strongly preferred.
• Internal medicine, clinical microbiology, pulmonology, intensive care or another relevant specialty may be considered if combined with deep anti-infective expertise.
• PhD, clinical research doctorate or equivalent academic track record is highly desirable.

Professional experience

• Typically 10+ years of combined clinical, academic and/or pharmaceutical development experience.
• Experience designing and leading multicenter interventional studies, preferably in infectious diseases or anti-infectives.
• Experience building multinational investigator networks and contributing to public, charitable or collaborative clinical-research funding applications is strongly preferred.
• Demonstrated clinical development experience from early phase through pivotal studies and registration.
• Experience with EMA and/or other health-authority interactions, GCP, medical monitoring and benefit-risk assessment.
• Publication record and recognized network among clinicians and KOLs.
• Experience with biologics, precision medicine, companion diagnostics or personalized therapies is advantageous.
• Bacteriophage experience is beneficial but not required.

Leadership profile

• Clinically credible, patient-centered and scientifically rigorous.
• Able to convert complex concepts into executable clinical programs.
• Strong communicator with investigators, regulators, employees, commercial colleagues and external stakeholders.
• Visible and persuasive medical ambassador, without compromising scientific accuracy or compliance.
• Comfortable in an entrepreneurial scale-up environment.
• Fluent professional English; French and/or Dutch are assets.